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Image Number 4 - Spleen, massive splenomegaly

In referring to an enlarged organ as hypertrophied, the underlying cause may be hypertrophy and/or hyperplasia of the individual cells (if the cells are capable of mitosis). Another very common example of the use of the term hypertrophy of an organ is in the case of benign prostatic hypertrophy, often referred to as BPH. In the case of BPH the underlying process is in fact hyperplasia. In the example seen in this slide, note the enlarged purple organ that is the spleen. Normally the spleen is tucked up underneath the rib cage, and is not palpable.

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