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Image Number 9 - Cervix, metaplasia, squamous metaplasia

Metaplasia is the reversible replacement of one type of adult tissue by another type of adult tissue. In this slide, note that the normal simple columnar epithelium of the cervix has been replaced by a stratified, non-keratinized, squamous epithelium. Another common example of metaplasia is the change from the normal respiratory epithelium in the airways to a stratified squamous epithelium as seen in a cigarette smoker. When the individual ceases to smoke the metaplasia will, in time, be reversed. There is no direct correlation between metaplasia and neoplasia. However, if the inducing agents of the metaplasia are carcinogenic then the metaplasia could progress to a neoplasia.

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