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URBANA ATLAS OF PATHOLOGY

Image Number 10 - Heart, necrosis and scar, papillary muscle

Necrosis is the result of the degradation of dead tissue. It is the result of the denaturation of proteins and the enzymatic digestion of the components of the cell. Necrosis does not require bacteria or other microorganisms to occur. Coagulative necrosis is the most common type and is due to ischemia in all tissues except the central nervous system. Liquefactive necrosis is seen primarily in the degradation of neural tissue, such as the brain and following bacterial infection. (Refer to the definitions and mechanisms of coagulative, liquefactive, fat, and caseous necrosis). In this slide, the area of coagulative necrosis has been replaced by a scar. The cause of the necrosis in this case is probably an infarct of the myocardium = heart attack. The scar is the white spot seen at the tip of the white pointer.

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