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Image Number 11 - Heart, necrosis

This is an example of coagulative necrosis. Cellular and tissue characteristics of early to mid-coagulative necrosis are the loss of nuclei from the muscle fibers, cytoplasmic eosinophilia with the maintenance of the cellular architecture. Notice that the nuclei that do remain are not within the cells and that they are pyknotic. Over time macrophages will phagocytose the dead tissue and the area will be replaced with collagenous tissue, a scar.

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