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Image Number 119 - Artery, syphilitic aortitis

The typical lesion of treponema pallidum infection is arteritis obliterans which results in painless lesions of the genitals initially and then&127; necrosis of the media of the vasculature at various sites in the body. This obliterative arteritis is especially profound when the vasa vasorum of the aorta are involved resulting in&127; ischemic necrosis of the media of the aorta. Necrosis is seen in this slide as the loss of pink muscle in the central area. The black represents the staining of the elastic tissue in the media. Such necrosis is the primary cause of proximal aortic aneurysm and has profound clinical consequences.

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