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Image Number 123 - Artery, polyarteritis nodosa

Polyarteritis nodosa (PAN) is an inflammatory necrotizing disease of the small and the medium sized arteries of the body. Histologically, it is characterized by fibrinoid necrosis of the arterial wall with a leukocytic infiltrate. In this slide, there is a large pale occlusion of a muscular artery. Within this collagenous tissue is a leukocytic infiltrate - this is the hallmark of PAN.

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