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Image Number 23 - Liver, alcoholism, fatty change

This is an example of alcoholic steatosis, which is fatty change of the liver due to acute or chronic consumption of large amounts of alcohol. The band of large white cells seen in the center of the field is composed of hepatocytes which have become filled with lipid. This is called macrovesicular fatty change. Normal sinusoids and cords of normal hepatocytes are seen in the bottom right and the upper left portions of the screen. Sometimes lipogranulomas occur with fatty change. However, none are seen here. Notice that inflammatory cells are not seen within the field of view. Therefore, this is not alcoholic hepatitis.

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