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Image Number 46 - Lung, hyaline membrane disease, respiratory distress

Hyaline membrane disease is also known as respiratory distress syndrome of the newborn and as adult respiratory distress syndrome (ARDS). The condition is characterized histologically by the presence of a hyaline membrane which lines the alveolar walls. This membrane is the result of a fibrinous exudate and the necrotic debris of cells. Other characteristics are the breakdown of the endothelial cells and the type 1 pneumocytes of the lung and the proliferation of the type 2 pneumocytes. In this slide, a hyaline membrane (glassy pink membrane) is seen lining the four alveoli that are visble. Note that the other alveoli are filled with RBCs and other cells.

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