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Image Number 60 - Peritoneal cavity, ascitic fluid, melanoma

Notice the prominent hyperchromatic nucleus at arrow 1 which characteristically contains a very prominent nucleolus. Arrow 2 indicates some of the eosinophilic cytoplasm. Arrow 3 highlights the pigment that is characteristic of melanomas. Melanocytes do not normally have visible melanin in them but export it to the surrounding keratinocytes. This cell was present in the ascitic fluid because it had metastasized. Metastatic cells are by definition malignant.

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