Lung, hyaline membrane disease

Hyaline membrane disease is also known as respiratory distress syndrome of the newborn and as adult respiratory distress syndrome (ARDS). The condition is characterized histologically by the presence of a hyaline membrane which lines the alveolar walls. This membrane consists of a fibrin exudate and the necrotic debris of cells. Other characteristics are the breakdown of endothelial and type1 cells and the proliferation of type 2 pneumocytes.

In this slide there is a hyaline membrane (glassy pink membrane) lining the 4 visible alveoli . Note that the other alveoli have been obliterated by RBCs and other cells.